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Dear Clinic · Treatments · Skin Boosters & Collagen Stimulators
The Full Arsenal

Skin Boosters & Collagen Stimulators in Cheongdam, Seoul

Five injectable materials doing four different jobs — polynucleotide, PDLLA, PLLA, calcium hydroxylapatite and hyaluronic acid. Because all five sit in the same clinic, the one you leave with is chosen from what your skin is short of.

5 booster materials compared Open 365 days English consultation
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Which skin booster is right for you?

Five injectable materials are sold under the words skin booster, and they do four different jobs. Polynucleotide works on the condition of the skin itself; PDLLA and PLLA ask your own collagen to rebuild; calcium hydroxylapatite acts as a scaffold; hyaluronic acid rehydrates a treated field. Dear Clinic keeps all five in the building, so the EVE Muse 3D + AI diagnosis names the material before anybody names a brand.

Most people arrive with the word "glow". It hides at least three separate findings: a surface that is dehydrated while the structure underneath it is intact, skin that has thinned structurally so light scatters badly and fine crepe appears where none used to be, and tissue that has deflated, which turns the complaint into a support problem and takes skin quality out of it altogether. Three findings, three different materials. Enthusiasm for one product does nothing about the other two.

This page is the map for that decision. Below you will find the five injectable boosters and collagen stimulators with a page of their own here, what each material physically is, the concern it genuinely addresses, and a side-by-side table of mechanism, downtime and starting price. Which of the five belongs to your face is settled by the scan; where the scan shows a healthy structure and a damaged barrier, we do not recommend an injectable at all, and you are told that at the consultation.

EVE Muse 3D and AI skin analysis device used to decide which skin booster material suits a patient at Dear Clinic
Material first, brand second — every booster plan starts at the EVE Muse 3D + AI diagnosis.
The Booster Arsenal

Five materials,
four separate jobs

Regeneration, collagen stimulation, structural scaffolding and pure hydration — four ideas across five injectables. Tap any one for its mechanism, protocol, aftercare and full published price.

All prices are published rates, identical for residents and international visitors. Volumes, vial counts and session intervals are set at diagnosis and approved by you before any needle is opened.

Side by Side

How the materials compare

Read the middle column first. Two of these rebuild collagen, one repairs, one scaffolds and one hydrates — and only one of those four is likely to be your finding.

InjectableMaterial & mechanismDowntimeHow the result developsFrom
JuvelookPDLLA microspheres in a hyaluronic-acid carrier — gradual collagen stimulation with an early carrier effectInjection points and short-lived swelling; small bumps possible while the carrier settlesTwo-stage: the carrier reads early, the collagen response accrues across a planned course₩100,000 (≈ $70) / 1 cc
Rejuran HealerPDRN — polydeoxyribonucleotide purified from salmon DNA, placed in fine deposits within the skinVisible injection points and transient raised deposits; bruising possibleJudged across a planned course, since the day itself shows only the injection points; the eye and HB lines are dosed separately₩300,000 (≈ $215) / 2 cc
SculptraPLLA — poly-L-lactic acid, reconstituted from a vial and placed deep as a collagen stimulusInjection points, swelling from the diluent, occasional bruising; massage instructions matterNothing on the day by design; restoration appears only as your own collagen is laid down and is reviewed between vials₩1,200,000 (≈ $855) / vial
RadiesseCaHA — calcium hydroxylapatite in carrier gel; neat for structural support, hyperdiluted for a firmness responseInjection points and swelling; a neat placement can feel firm at firstImmediate support when placed neat; gradual and diffuse when hyperdiluted across a plane₩1,200,000 (≈ $855) / vial
SkinviveHyaluronic acid delivered as micro-droplets within the skin — hydration of a field, not projection of a contourAmong the lightest here: pinpoint marks and brief rednessSurface quality reads early in the treated field; repeated on a maintenance rhythm set at review₩450,000 (≈ $320) / 1 cc

How a result develops varies with individual skin, age, area and lifestyle; the descriptions above are patterns and promise nothing. Volumes and vial counts are planned per face, so the table shows base units and never a finished quote.

Head-to-head booster guides

Radiesse has no head-to-head guide here because nothing else on this page is calcium hydroxylapatite; the Radiesse page sets out neat and hyperdiluted use in full.

Dear, Knowhow

Why plan a booster course at Dear

01 — THE FULL ARSENAL

All five materials on one trolley

Polynucleotide, PDLLA, PLLA, calcium hydroxylapatite and hyaluronic acid are all stocked here. None of them needs your face to justify its purchase. That is what makes "nothing injectable this year" a sentence you can actually be told.

02 — DIAGNOSIS FIRST

Five light sources, one baseline

Three-dimensional imaging under five light sources separates hydration from structure, and structure from lost support, which is the exact fork that decides between hydration, repair, collagen stimulation and scaffolding. The capture is kept on file, so the review at the end of your course compares two measurements.

03 — DIRECTOR-PERFORMED

A millimetre decides which way it goes

These materials behave completely differently a millimetre apart: too superficial and a stimulator leaves a lump, too deep and a booster wastes its effect. Your injections are performed by the director who read your scan and set the plan, with review appointments built into the course instead of billed as extras.

Consultation room at Dear Clinic where skin booster materials are chosen with the patient
The material is chosen here, with the scan on screen — before any product is brought into the room.
Treatment room at Dear Clinic in Cheongdam used for skin booster and collagen stimulator injections
Injection room — single-use materials, prepared and placed by your own director.
In the clinic

The devices and hands behind this treatment

Sculptra 367.5 mg single vial with its reflection on a transparent background
Sculptra 367.5 mg single vial with its reflection on a transparent background
Skinvive by Juvederm carton floating between two blue discs
Skinvive by Juvederm carton floating between two blue discs
Skin booster consultation visual
Skin booster consultation visual
The Method

How a booster prescription is decided

Four steps, in this order — and the product name only appears at step three.

01

Name the finding

The scan and the five-light analysis sort your concern into a category: surface dehydration, damaged or thinned skin quality, lost collagen structure, or genuine loss of underlying support. Most people arrive convinced of one and leave with a different answer.

02

Match material to finding

Each finding maps to a material class before it maps to a brand. Hydration points to hyaluronic acid; skin condition points to polynucleotide; lost collagen points to a lactic-acid stimulator; deflation or a need for structural support points to CaHA. Usually one or two of the five survive.

03

Set the dose and the rhythm

Now the injectable is named, and with it the numbers: volume per area, vials, depth, and how the sessions are spaced. Where two materials genuinely complement each other — repair now, collagen later — the sequence and the interval are planned as one course and quoted as one course.

04

Inject, then review the field

Your director performs the session, then reviews at the interval the mechanism deserves. Collagen work is judged over a course, and the morning after tells you nothing. The following session is confirmed only when the review says it earns its place.

If your diagnosis shows that a good skincare routine and sun protection would do more for you this year than any injectable, that is what you will be told. Declining to treat is part of the same method.

Medical Team

Five doctors, one standard

Director-performed treatment is a Dear promise — your procedure is planned and performed by the doctors below.

Dr. Jemin Kim — Medical Director and Founder, Dear Clinic
Dr. Jemin Kim
Yonsei University College of Medicine
Medical Director · Founder
Dr. Sanghyun Lee — Director, Dear Clinic
Dr. Sanghyun Lee
Seoul National University College of Medicine
Director
Board-certified · Family Medicine
Dr. Seonhaeng Lee — Director of Aesthetic Medicine, Dear Clinic
Dr. Seonhaeng Lee
Chosun University College of Medicine · Residency, Samsung Medical Center
Director, Aesthetic Medicine
Dr. Daeun Jung — Director, Dear Clinic
Dr. Daeun Jung
Ajou University College of Medicine
Director
Board-certified · Family Medicine
Dr. Woojae Jung — Director of Aesthetic Medicine, Dear Clinic
Dr. Woojae Jung
Seoul National University — B.S. in Medicine
Director, Aesthetic Medicine
Patient Reviews

What our patients say

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FAQ

Skin boosters in Seoul, answered

Which skin booster is right for me?
The one whose material matches your finding. If the complaint is a dull, thirsty-looking surface, hyaluronic acid delivered as micro-droplets is the direct answer. If the skin itself is damaged or thin, polynucleotide is the repair-oriented choice. If collagen has been lost, a lactic-acid stimulator rebuilds it slowly. If the face has deflated or needs structural support, calcium hydroxylapatite belongs in the conversation. Because Dear Clinic carries all five, the EVE Muse 3D diagnosis decides — and you approve the plan before anything is drawn up.
What is the difference between a skin booster and a filler?
A filler is placed to hold a shape: it sits in a planned pocket and projects a chin, a bridge or a fold. A booster is spread through the skin or the tissue plane to change quality, hydration or collagen content, and it is not trying to alter your outline at all. The confusion is understandable because some of the same materials appear in both categories — hyaluronic acid, for instance, does both jobs in different formulations. Which category you belong in is the first question your director settles.
How much do skin boosters cost in Seoul?
Published base units at Dear Clinic start at ₩100,000 (≈ $70) per cubic centimetre for Juvelook and ₩300,000 (≈ $215) for a 2 cc Rejuran Healer session, with hyaluronic-acid boosting from ₩450,000 (≈ $320) per cubic centimetre and vial-based collagen stimulators from ₩1,200,000 (≈ $855). Specialty areas and the eye-specific lines are priced separately. These are published rates, identical for residents and international visitors, and your total is confirmed once the volume and session count are planned.
Is Rejuran the same as the "salmon DNA" injection people talk about?
Yes — that popular nickname refers to PDRN, polydeoxyribonucleotide, a purified polynucleotide fraction derived from salmon DNA and the active ingredient in Rejuran Healer. Nothing about the name implies a fish product is injected as such; the material is a purified fraction manufactured to pharmaceutical standards by PharmaResearch. The line also includes eye-specific and HB variants, which are dosed and priced separately because the skin around the eye behaves differently.
Can I combine two boosters, or a booster with a lifting treatment?
Often, and combining is one reason to choose a clinic that carries the whole range. Repair-oriented and collagen-stimulating materials answer different findings, so a face short of both may be planned as a sequence with a set interval. Boosters also pair naturally with energy-based lifting, since one works on skin quality while the other works on laxity. What matters is that the combination follows a finding; a package price is never a clinical reason.
How much downtime should I expect?
Less than most people fear, but it is not zero. Expect visible injection points, brief redness and the possibility of bruising for a few days — makeup usually covers the marks the following day. Polynucleotide deposits can be briefly raised where they were placed, and collagen stimulators can swell from their diluent before settling. Hyaluronic-acid boosting is the lightest of the group. Saunas, alcohol and vigorous exercise are best postponed briefly after any of them.
When will I see a change?
It depends on the material. Hydration-led treatments read earliest, in the treated field. Collagen stimulators are the opposite: by design nothing appears on the day, and the change arrives only as your own collagen is laid down across a planned course. Repair-oriented boosters are judged over a course as well, which is why your director fixes the review date at the first appointment instead of quoting you a week number. Individual results vary with skin, age and lifestyle.
I have never had an injectable. Where should I start?
Start with the diagnosis. Which product your feed recommends is the least useful input in the room. In practice a first-timer whose finding is surface quality often begins with a hydration-led or repair-oriented booster: both are conservative, both simply wear off, and both are easy to build on. Collagen stimulators cost more, take months to read and commit you to a course, so they usually belong to a second conversation.
Can I have a booster the same day as my consultation?
Usually yes for a hydration-led or repair-oriented booster: diagnosis and consultation take about thirty minutes, and the injection can follow once your director confirms suitability. A vial-based collagen stimulator is a different proposition, because the first session starts a staged course, and we ask you to take that plan away and decide at home. The clinic is open 365 days a year including Sundays and public holidays, so a Sunday slot is an ordinary booking. Leave a day or two before an event; injection points need it.
Are prices the same for international visitors, and how do I book from abroad?
One published price list applies to everyone, shown in Korean won with a US dollar figure for reference; you can review it on our price list page, and our 365-day opening page explains weekend and holiday scheduling. Boosters are quoted by unit — per cubic centimetre, per 2 cc session or per vial — so tell us your travel dates and your main concern on the form below and we will say which units your question is likely to involve. We reply in English within one business day and hold the slot without a deposit.
Consultation

Ask about skin boosters

Your questions, answered in English within one business day.

Scientific Evidence

Science behind skin boosters & collagen stimulators — peer-reviewed references

The materials on this page belong to three separate research literatures: polynucleotides, lactic-acid collagen stimulators, and calcium hydroxylapatite. Grouping them under one marketing word does not merge their evidence, so the references below are cited by material rather than by category.

All references carry verifiable DOIs from indexed journals, and each informs a different part of the decision your director makes after the EVE Muse 3D + AI diagnosis.

  1. Hong J et al. Therapeutic Performance of Needle Injection Versus Needle‐Free Jet Injector System for Polynucleotide Filler in Skin Rejuvenation. Journal of Cosmetic Dermatology. 2024. doi:10.1111/jocd.16595
  2. Fitzgerald R et al. Facial volume restoration of the aging face with poly-l-lactic acid. Dermatologic Therapy. 2011. doi:10.1111/j.1529-8019.2010.01375.x
  3. Goldie K et al. Global Consensus Guidelines for the Injection of Diluted and Hyperdiluted Calcium Hydroxylapatite for Skin Tightening. Dermatologic Surgery. 2018. doi:10.1097/dss.0000000000001685

References are provided for information — outcomes vary by individual and are assessed at your diagnosis.

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