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Dear Clinic · Procedure Comparison · Collagen Stimulators
PLLA vs PDLLA

Sculptra vs Juvelook

Two collagen stimulators that both ask your skin to rebuild itself — one built on poly-L-lactic acid and sold by the vial, one a poly-D,L-lactic acid and HA hybrid dosed by the cc. Different scale, different control. Which one fits depends on what your face has actually lost.

Both in-house at Dear Diagnosis-led recommendation Open 365 days
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Short Answer

Sculptra or Juvelook — which?

Sculptra is a PLLA collagen stimulator — poly-L-lactic acid from Galderma — planned and priced by the vial, and generally chosen when a face needs structural volume rebuilt across a broad area. Juvelook is a PDLLA + HA hybrid from VAIM, dosed by the cc, that stimulates collagen gradually while improving fine lines, pores and skin texture. Sculptra rebuilds volume across a zone. Juvelook works on texture and adds a modest amount of volume with it.

Neither is a hyaluronic-acid filler in the ordinary sense. A filler occupies space the moment it is placed; these two ask your own collagen to do the work over the following months, so the change arrives slowly and reads as structural. Scale and control are the practical difference. A vial of PLLA is an area-scale plan. A cc of the PDLLA hybrid is a finer instrument that can be aimed at texture as much as at volume, which is why the two are dosed in different units in the first place. Researchers have measured the gap directly — one of the studies listed below compares the early-stage volume effect of injectable poly-l-lactic acid with injectable poly-d,l-lactic acid — so the distinction is documented, and specific enough that a diagnosis should decide it.

Side by Side

Sculptra vs Juvelook, compared

Ingredient, unit, target and published price — set out plainly so the decision is yours to make.

  Sculptra Juvelook
Active material PLLA — poly-L-lactic acid PDLLA (poly-D,L-lactic acid) + HA hybrid
Manufacturer Galderma VAIM
Planning unit Per vial Per cc
How it works Gradual stimulation of your own collagen Gradual collagen stimulation, long-lasting
Usually chosen for Structural volume rebuilt over a broad area Fine lines, pores, skin texture and natural volume
Character of the change Slow, architectural, area-scale Slow, finer-grained, surface and volume together
Category Collagen stimulator — PLLA carries no HA Collagen booster with an HA carrier
Also on the shelf Other biostimulators for different indications Juvelook Volume dosing, with a separate specialty-area rate
At Dear, from ₩1,200,000 (≈ $855) / vial ₩100,000 (≈ $70) / 1cc
How much do Sculptra and Juvelook cost in Seoul? At Dear Clinic in Cheongdam, Sculptra is ₩1,200,000 (≈ $855) per vial and Juvelook is ₩100,000 (≈ $70) per cc, with specialty-area dosing priced separately. The per-cc figure is the published Juvelook Volume rate; specialty areas carry their own. These are published prices, identical for residents of Seoul and for international visitors, and the number of vials or cc in your plan is agreed with you before anything is drawn up.

Because the two are sold in different units, comparing headline numbers alone is misleading — a vial and a cc are not the same quantity of work. What matters is the total your director plans for your face, which you see and approve at consultation. There are no visitor surcharges and nothing is added on the day.

By Your Case

PLLA or PDLLA for your case

Three patterns that arrive at the consultation desk, and the material each one points to.

CASE 01 — SCULPTRA

The face has lost its scaffolding

Temples flattening, cheeks reading hollow under side light, a face that looks tired at rest while the lines themselves are still shallow. The shortfall is structural and spread across several regions. A vial-scale PLLA plan is the instrument built for that scale of rebuilding, and one crease on its own is not a reason to open a vial.

CASE 02 — JUVELOOK

Texture and firmness in one pass

Enlarged-looking pores, fine crepiness, skin that has lost bounce but not yet its shape. Dosed by the cc, the PDLLA and HA hybrid can be aimed at skin quality and subtle volume in the same pass. People ask for it when they want their skin to look better without their face looking fuller.

CASE 03 — STAGED

Structure first, then surface

Some faces need both jobs done, in a set order. Rebuilding the underlying volume first and refining texture afterwards gives each material one clear task and keeps the total conservative. Both sit on our shelf, so the stages can be spread across months instead of one product being asked to do everything.

Laser treatment room at Dear Clinic Cheongdam with several laser platforms and a powered treatment chair
Laser treatment room at Dear Clinic Cheongdam with several laser platforms and a powered treatment chair
Procedure room at Dear Clinic with radiofrequency and ultrasound body-contouring systems
Procedure room at Dear Clinic with radiofrequency and ultrasound body-contouring systems
Before & After

A Dear Juvelook case

One unretouched case treated at Dear Clinic, shown with consent. We publish only the cases we hold — there is no Sculptra photo on this page, and we will not label someone else's result as one. Individual results vary.

Juvelook collagen booster before and after — same patient, same lighting, firmer and smoother skin, Dear Clinic case
Juvelook · before / after — same person, same conditions, firmer skin with refined texture

This is an unretouched before/after case of the same person under the same conditions, treated at Dear Clinic and shown with consent. The photo shows only the treatment it is labelled with. Individual results may vary; no specific outcome is implied or promised.

The Combination

Why the order matters

These materials work slowly, and stacking sessions does not speed them up. A sensible way to stage them:

Sculptra's poly-L-lactic acid is planned by the vial, so it is the instrument for area-scale structural work.
Juvelook's PDLLA and HA hybrid is dosed by the cc, so it is the instrument for finer, quality-led correction.
Doing the structural work first gives the surface work a stable base to sit on.
Intervals are spaced deliberately — collagen answers on its own timetable, and stacking sessions does not hurry it.
The plan is reviewed as the response appears, so the date of the next session comes from your skin and not from a package agreed in advance.

Boosters, stimulators and the HA filler lines are all stocked in-house, so a plan here can be Sculptra, Juvelook, both in sequence, or neither of them.

Consultation room at Dear Clinic where collagen stimulator plans are designed after 3D diagnosis
Where the choice is actually made — the consultation room, after your diagnosis.
Dear, Knowhow

Deciding between PLLA and PDLLA at Dear

01 — THE FULL ARSENAL

Both materials, one shelf

Sculptra by the vial and Juvelook by the cc are both stocked here, alongside the HA filler lines and the wider booster range. Waiting is therefore a recommendation we can afford to make.

02 — DIAGNOSIS FIRST

The scan separates volume loss from texture loss

EVE Muse 3D imaging under five light sources tells lost volume apart from lost skin quality — two findings that look identical in a mirror and call for different materials. The reading sets the plan, together with a hands-on examination of where the skin has actually thinned.

03 — DIRECTOR-PERFORMED

Depth, dose and restraint per pass

With biostimulators the plane of injection and the amount left at each pass decide how the result reads six months later; too much material in one sitting is what produces the lumps and over-correction these stimulators are known for, and neither can be dissolved the way an HA filler can. Every session is performed by our directors at conservative amounts per pass, and the response is reviewed before anything more is added.

In the clinic

The devices and hands behind this treatment

Sculptra 367.5 mg single vial with its reflection on a transparent background
Sculptra 367.5 mg single vial with its reflection on a transparent background
Juvelook MEISTER crystal award— Juvelook (VAIM)
Juvelook MEISTER crystal award— Juvelook (VAIM)
Reception seen from the opposite angle with the arc floor lamp at Dear Clinic Cheongdam
Reception seen from the opposite angle with the arc floor lamp at Dear Clinic Cheongdam
Declining

When we decline a stimulator

A collagen stimulator is a poor answer to the wrong question. Skin that is genuinely lax often needs a lifting treatment before any injectable; a single deep crease is usually a filler problem. Dullness after a hard month is frequently a sleep and routine problem, and we do not recommend a vial or a cc for it. Pick the wrong material and you lose months finding out, because the response is slow by design and there is nothing to dissolve if you change your mind. Swelling, small bumps and bruising at the injection points are the ordinary short-term risks; lumps or nodules from over-correction are the ones worth avoiding, and conservative dosing is how they are avoided.
01
Collagen-led firmness
02
Refined skin texture
03
Restored facial volume
04
Gradual, natural change

Outcomes and suitability vary by individual and are assessed at your in-person diagnosis. A published price list covers every item discussed here.

Entrance of Dear Clinic in Cheongdam, Gangnam, Seoul, with the clinic hours shown in English on the glass door
Entrance of Dear Clinic in Cheongdam, Gangnam, Seoul, with the clinic hours shown in English on the glass door
EVE Muse AI analysis screen showing multi-angle facial capture
EVE Muse AI analysis screen showing multi-angle facial capture
Caution

After a Sculptra or Juvelook session

Keep cleansing and make-up gentle for a day or two — minimal friction on the treated skin.
Occasional redness or a temporary blemish can appear afterwards and settles on its own.
Skip scrubs and exfoliating care for about a week after the session.
Washing and make-up are fine on the day itself, but avoid peeling treatments while the skin recovers.
Hold off on alcohol and smoking for around a week — both raise the risk of inflammation. A firm spot that does not settle, or new swelling after the first days, is a reason to call the clinic and be seen.
Medical Team

Five doctors, one standard

Director-performed treatment is a Dear promise — your procedure is planned and performed by the doctors below.

Dr. Jemin Kim — Medical Director and Founder, Dear Clinic
Dr. Jemin Kim
Yonsei University College of Medicine
Medical Director · Founder
Dr. Sanghyun Lee — Director, Dear Clinic
Dr. Sanghyun Lee
Seoul National University College of Medicine
Director
Board-certified · Family Medicine
Dr. Seonhaeng Lee — Director of Aesthetic Medicine, Dear Clinic
Dr. Seonhaeng Lee
Chosun University College of Medicine · Residency, Samsung Medical Center
Director, Aesthetic Medicine
Dr. Daeun Jung — Director, Dear Clinic
Dr. Daeun Jung
Ajou University College of Medicine
Director
Board-certified · Family Medicine
Dr. Woojae Jung — Director of Aesthetic Medicine, Dear Clinic
Dr. Woojae Jung
Seoul National University — B.S. in Medicine
Director, Aesthetic Medicine
Patient Reviews

What our patients say

Real verified reviews from our Google Business Profile.

4.9★★★★★ 293 Google Reviews
FAQ

Sculptra vs Juvelook, answered

What is the difference between Sculptra and Juvelook?
Sculptra is poly-L-lactic acid (PLLA) from Galderma, planned by the vial, and it is generally used to rebuild structural volume across a broad area. Juvelook is a poly-D,L-lactic acid and hyaluronic-acid hybrid from VAIM, dosed by the cc, and it works on fine lines, pores and skin texture while adding natural volume. Both stimulate your own collagen gradually. They differ in scale, in unit, and in what they are aimed at.
Which one is better for hollow cheeks and lost volume?
When the shortfall is structural — flattened temples, cheeks that read hollow, a face that looks drawn at rest — the vial-scale PLLA plan is usually the more direct route, because it is built for area-scale rebuilding. Juvelook can add natural volume too, but at cc scale it is a finer instrument. The EVE Muse 3D scan measures where the volume actually went before either is recommended.
Which is better for pores, fine lines and skin texture?
Juvelook. Its PDLLA and HA hybrid is asked to improve fine lines, pores and skin texture while forming natural volume, which is exactly the quality-led brief. Sculptra's poly-L-lactic acid is aimed at structure rather than surface. If your goal is skin that looks refined without your face looking fuller, the PDLLA route fits better.
Are Sculptra and Juvelook fillers?
Not in the ordinary sense. A hyaluronic-acid filler occupies space the moment it is placed and can be dissolved with hyaluronidase; these two ask your own collagen to build over the following months, so the change appears slowly and there is nothing to dissolve if you change your mind. If your concern is a single crease or an immediate contour change, an HA filler is the better recommendation.
How many vials or cc will I need?
The plan is written per face; there is no fixed course to buy. Your director sets the number of vials or cc and the interval from your diagnosis, then reviews the plan as your collagen response appears, so the next session follows what your skin has done. You approve each stage and its total before it goes ahead.
How much do Sculptra and Juvelook cost in Seoul?
At Dear Clinic, Sculptra is ₩1,200,000 (≈ $855) per vial and Juvelook Volume is ₩100,000 (≈ $70) per cc, with specialty-area dosing at its own published rate. Because a vial and a cc are different quantities of work, compare the planned total rather than the headline figures. Both are published prices, identical for locals and international visitors, and approved by you before treatment.
Can I have both, or switch from one to the other?
Yes, and staging them is common: structural work first, surface refinement afterwards, spaced so each material has time to answer. Switching is equally reasonable if your diagnosis changes, since nothing commits you to a product. Both are in-house here, so the sequence is designed around your face and not around what happens to be available.
Is a collagen stimulator worth it for me?
Ask your director to show you, on the 3D scan, whether what you dislike is lost volume or lost skin quality. If it is neither — if the finding is laxity, or one deep fold — a stimulator is the wrong purchase and we will say so. If it is either, the category is built for it, and the scan indicates which of the two materials applies. What a stimulator cannot give you is a visible change this week.
What does the session feel like, and is there downtime?
Fine-needle injections, made comfortable with topical numbing applied beforehand; most people describe brief pinching and some pressure as the material is distributed. Afterwards expect mild redness, small injection bumps or slight tenderness, usually settling within a day or two. Keep cleansing gentle, skip scrubs for about a week, and hold off on alcohol, smoking and saunas briefly. Most people return to their normal plans the same day.
How long do the results last?
Both build gradually as collagen forms, and Juvelook is characterised by its manufacturer as long-lasting for that reason. How long any individual keeps the result depends on age, skin condition and lifestyle, so we do not quote a fixed figure on a web page. Your director gives you a realistic expectation for your own plan at consultation and revises it as the response develops.
Can I start a stimulator plan on the day I arrive in Seoul?
Usually yes. The EVE Muse 3D diagnosis and doctor consultation take about 30 minutes, and a first vial or first cc can follow immediately once your director confirms suitability. What a short trip cannot compress is the collagen response itself, so if you are here for four days, plan on flying home before the change is visible. Dear Clinic is open 365 days a year, including Sundays and public holidays.
Is the price the same for international visitors, and how do I book from abroad?
One published price list covers residents and visitors alike; KRW is what you pay and USD is shown for reference. Send the consultation form below with your travel dates and we reply in English within one business day, holding your slot without a deposit. Tell us how long you are in Korea: a staged Sculptra-then-Juvelook plan needs months, and if your trip is short we will tell you which single step is worth doing now and which is better started at home.
Consultation

Ask which stimulator fits your face

Your questions, answered in English within one business day.

Scientific Evidence

Science behind PLLA & PDLLA — peer-reviewed references

Choosing between a poly-L-lactic acid stimulator and a poly-D,L-lactic acid hybrid rests on a body of peer-reviewed literature about lactic-acid biostimulators — volume restoration, volumetric correction, biostimulatory activity and, in one study, a direct comparison of the early-stage volume effect of the two acids. The references below inform how our directors match a material to your face after the EVE Muse 3D and AI diagnosis.

All references carry verifiable DOIs from indexed journals. Titles, journals and years are reproduced as published; outcomes vary by individual and are always assessed in person.

  1. Fitzgerald R, et al. Facial volume restoration of the aging face with poly-l-lactic acid. Dermatologic Therapy. 2011. doi:10.1111/j.1529-8019.2010.01375.x
  2. Vleggaar D. Facial Volumetric Correction with Injectable Poly‐l‐Lactic Acid. Dermatologic Surgery. 2005. doi:10.2310/6350.2005.31236
  3. Lin J, et al. Early‐stage volume effect difference between injectable poly‐l‐lactic acid and injectable poly‐d,l‐lactic acid. Journal of Cosmetic Dermatology. 2022. doi:10.1111/jocd.15595
  4. Angelo-Khattar M. Poly-L-Lactic Acid in Facial Rejuvenation: Volumetric Data Supporting Regenerative Outcomes. Clinical, Cosmetic and Investigational Dermatology. 2025. doi:10.2147/ccid.s566829
  5. Arruda S, et al. A Clinical Histology Study Evaluating the Biostimulatory Activity Longevity of Injectable Poly-L-Lactic Acid for Facial Rejuvenation. Journal of Drugs in Dermatology. 2024. doi:10.36849/jdd.8057

References are provided for information — outcomes vary by individual and are assessed at your diagnosis.

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